The development occupies an island site with frontages to New Cavendish Street, Great Titchfield Street, Clipstone Street and Hanson Street.

101 New Cavendish Street is superbly located for cross London access, being within easy walking distance of eight tube stations. These in turn provide access to all the Central London main rail terminals without the need to change lines.

Consequently, connectivity to all of the London Airports is excellent.